This Week in Startups
Jason Calacanis covers startups, tech, markets, media, and all the hottest topics in business and technology. He also interviews the world’s greatest founders, operators, investors, and innovators.
148 transcripts
148 total episodes
This Week in Startups
The Pentagon Wants Equity in AI Startups | E2336
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This Week in Startups
Becki DeGraw on founder vesting, advisor equity & the 4-term-sheet play
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This Week in Startups
Did OpenAI Steal the Navier-Stokes Solution? | E2335
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This Week in Startups
Dr. Mark Hyman on Function Health & GLP-1 microdosing | E2334
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This Week in Startups
Becki DeGraw on spinouts, IP licensing & clean exits | Wilson Sonsini Startup Legal Basics
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This Week in Startups
VC experts on why Physical AI funding is heating up | E2333
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This Week in Startups
Are AI Agents forming "civilizations" or is this just a psy op? | 2332
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This Week in Startups
Breaking down Nvidia's Hugging Face and Poolside bets | E2331
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This Week in Startups
Bill Gates foresees massive AI job loss: these VCs disagree | E2330
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This Week in Startups
You Can't Fire a VC From Your Board: Here's Why | Wilson Sonsini Startup Legal Basics
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This Week in Startups
China wants you to cheer for the robots taking your job | E2329
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This Week in Startups
Open source is going to win it all: Harvey proves it | E2328
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This Week in Startups
Taste is the new programming language (w/ Astrocade CEO Amir Sadeghian) | AI Basics
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This Week in Startups
Neurosymbolic AI outperforms chatbots and product search | E2327
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This Week in Startups
Bittensor creator Const on Affine, dTAO, "mining reasoning," and more | E2326
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This Week in Startups
What we'll learn from Anthropic's $2-$3T IPO | E2325
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This Week in Startups
These robots could cut delivery costs by 80% | Next Unicorns
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This Week in Startups
Zuck's AI manifesto is a data center PR masterclass | E2323
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This Week in Startups
How AI splits startups into winners and losers | E2322
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This Week in Startups
Airtable's 80% off value crash: VCs explain why it's still a win | E2321
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This Week in Startups
How Bespoke faked AI until it actually worked (w/ Akemi Tsunagawa) | E2320
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This Week in Startups
Why AI has no taste and how to fix it (w/ Thais Castello Branco) | E2319
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This Week in Startups
Banning Chinese robots isn't regulatory capture | E2318
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This Week in Startups
While other cultivated meat companies are collapsing, this one turned a profit | E2317
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This Week in Startups
Why quantum has been "10 years away" for 30 years | E2316
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This Week in Startups
Why this longevity startup raised in Japan, not Silicon Valley | TWiST Tokyo | E2315
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This Week in Startups
An AI that watches your every click may be the future of work | E2314
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This Week in Startups
The dawn of surgery bots + buy a home for $250 (w/ Andromeda & Mogul) | E2313
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This Week in Startups
A Startup Is Trying to Buy PayPal… Craziest Deal of 2026! | E2312
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This Week in Startups
Jason turned $11 and one tweet into 1.1M views | E2311
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This Week in Startups
Danny Bernstein left Big Tech to fund farm-bots | E2310
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This Week in Startups
Why Data Is the Next $1 Trillion Market
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This Week in Startups
$100T is managed by “human duct tape” | E2308
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This Week in Startups
Why the VC Hype Cycle Always Gets It Wrong | VC Roundtable | E2307
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This Week in Startups
Chamath on why young people need more agency, risk, and adventure
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This Week in Startups
Why F1 Teams are Replacing Wind Tunnels with Smart Tape | E2305
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This Week in Startups
Why the Future of Video Games is Moving Back to the Dinner Table
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This Week in Startups
The hottest running app has nothing to do with speed | E2303
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This Week in Startups
Why SpaceX Buying Cursor Changes Everything
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This Week in Startups
The Startup Building the First Hotel on the Moon…
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This Week in Startups
SpaceX IPO Day: What Wall St. and the media missed | E2300
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This Week in Startups
Why the most expensive Seed deals are the cheapest | E2299
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This Week in Startups
The AI Tutor That Makes Kids Actually Think | E2298
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This Week in Startups
Anthropic wants to slow AI down and Bernie wants 50%: JCal Reacts | E2297
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This Week in Startups
The Startup Turning Space Into a Logistics Network
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This Week in Startups
This Startup Fused Human Brain Cells with Silicon Chips | E2295
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This Week in Startups
How to Raise a Seed Round in 2026: Ask Jason | E2294
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This Week in Startups
The Drone Company Quietly Taking Over Delivery
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This Week in Startups
From hypercars to cruise missiles: Lukas Czinger on the future of US defense | E2292
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This Week in Startups
Avi Patel on the startup that copied Kled and why he called out General Catalyst by name | E2291
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This Week in Startups
Why is Gen Z hates AI?
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This Week in Startups
The Self-Driving Startup Nobody Saw Coming | E2289
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This Week in Startups
How Many Startups Will Survive OpenAI? | E2288
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This Week in Startups
Cerebras's IPO goes vertical, and the death of OpenClaw? | E2287
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This Week in Startups
5,000+ Tech Workers Laid Off This Week. It's Just The Beginning. | E2286
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This Week in Startups
The end of Venture Capital? (VC Roundtable) | E2285
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This Week in Startups
Naval's GP, Ankur Nagpal, Breaks Down The Viral “USVC” Fund | E2284
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This Week in Startups
Can an AI Agent Legally Own a Company? Christian van der Henst's Wild Experiment| E2283
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This Week in Startups
Mastering AI Video Marketing w/ Magnific CEO Joaquín Cuenca Abela | AI Basics
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This Week in Startups
The $10M+ Bet on a Beanie That Reads Your Brain | Sabi & the Future of BCI | E2282
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This Week in Startups
To the left of this of thumbnail i want to add a chinese flag to the left destroying the meta logo. because the title is China Kills Meta / Manus Deal (Story Of The Year) | E2281
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This Week in Startups
Naval’s $500 VC fund, the Maduro Polymarket scandal, and NYT defends theft and murder | E2280
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This Week in Startups
The Defense Tech Startup YC Kicked Out of a Meeting is Now Arming America | E2280
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This Week in Startups
SpaceX and Cursor team up to topple Claude Code | E2279
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This Week in Startups
Why Your Company Should Own Its AI Model | E2278
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This Week in Startups
3D-Printed Homes for $99K: ICON’s Jason Ballard on the future of housing | E2277
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This Week in Startups
This 22-Year-Old Built TikTok for Mobile Games, and It’s Growing Fast | E2276
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This Week in Startups
Bittensor’s (alleged) $10M rug pull (feat. Mark Jeffrey) | E2275
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This Week in Startups
Bittensor Drama! TAO down 15%! | E2274
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This Week in Startups
Anthropic’s Mythos is a cyber-weapon, so you can’t have it | E2273
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This Week in Startups
3 AI Agents That Actually Replaced Human Jobs | E2272
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This Week in Startups
AI Rebuilt Every YC W26 Startup. Should Founders Be Scared? | E2271
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This Week in Startups
How 3 CEOs Use AI to Run $10B in Companies | This Week in AI
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This Week in Startups
Venture Roundtable: SpaceX IPO, AI's PR Crisis, and the Defense Tech Bubble | E2270
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This Week in Startups
The 5-Step Framework for AI Agents That Improve While You Sleep | E2269
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This Week in Startups
The $60 billion resource hiding in space, and the start trying to mine it (feat. Matt Gialich, Astroforge) | E2268
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This Week in Startups
This Bittensor Subnet Could Cut Drug Discovery Costs in HALF | E2267
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This Week in Startups
$2.5B Chip Heist, The Future of American AI, and Purpose-Built Robots | This Week in AI Ep 6
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This Week in Startups
Compliance Startup Scandal... Is Delve Guilty? | E2266
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This Week in Startups
The Drone Company Everyone Thought Was Illegal (Now Worth $4B+) | E2265
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This Week in Startups
How Robinhood became a $68B company w/ Vlad Tenev
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This Week in Startups
Are Brain-Computer Interfaces Actually Ready for Humans?
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This Week in Startups
One Genius Rule That Made This Coffee Brand Famous | EP 2262
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This Week in Startups
The Global Expansion of Self-Driving Vehicles
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This Week in Startups
How agents will change banking forever | E2260
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This Week in Startups
Wisdom of the $TAO: the future is decentralized AI
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This Week in Startups
Is Anthropic Making the Biggest Mistake in AI History | E2258
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This Week in Startups
How the OpenClaw foundation bullet-proofed its future (w/Dave Morin) | E2257
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This Week in Startups
The Biggest Private Funding Round in History | E2256
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This Week in Startups
Behind the Scenes with an early OpenClaw contributor! | E2252
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This Week in Startups
Kill Your Startup’s Knowledge Chaos with OpenClaw (with Oliver Henry and Jeff Weisbein) | E2254
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This Week in Startups
We Asked 3 Experts How to Get More Value out of OpenClaw | E2253
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This Week in Startups
When Will Openclaw go Mainstream? | E2252
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This Week in Startups
Will OpenAI Tank OpenClaw? | E2251
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This Week in Startups
OpenClaw is Our Friend Now | E2250
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This Week in Startups
Why J-Cal Invested to 200K in a former Employee | E2249
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This Week in Startups
How These 3 Founders are building on Open Claw | E2248
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This Week in Startups
Does Clawdbot (OpenClaw) Need Eyes? (feat. Alex Finn and Matt Van Horn) | E2247
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This Week in Startups
We built OpenClaw Ultron to replace 20 people at our company | E2246
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This Week in Startups
Savvy is HQ Trivia + Wordle (feat. Scott Rogowsky) | E2245
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This Week in Startups
Where early-stage founders MUST focus to success | E2244
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This Week in Startups
SpaceX + xAI deal gets us one step closer to Musk Industries | E2243
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This Week in Startups
AI Bots Take Over | E2242
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This Week in Startups
How decriminalization led to an explosion in cannabis startups (Feat. Ford Smith, Andrew Duffy, and Socrates Rosenfeld) | E2241
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This Week in Startups
Clawdbot is an inflection point in AI history | E2240
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This Week in Startups
Why You’ll Choose an AI Doctor (feat. Fred Almeida and Max Weiss) | E2239
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This Week in Startups
From Blood Transfusions to Burritos, How Zipline is Automating Delivery | E2238
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This Week in Startups
How startups suddenly became “cool” in Japan (feat. Shin Takamiya of Globis Capital) | E2237
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This Week in Startups
Avoiding buzzwords and marketing-speak (feat. Thomas McInerney) | E2236
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This Week in Startups
Japan’s Startup Revolution (feat. Kathy Matsui) | E2235
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This Week in Startups
How to Make Billions from Exposing Fraud | E2234
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This Week in Startups
Secrets of Startup Recruiting in the US AND Japan! (feat. Sho Takei) | E2233
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This Week in Startups
Jason’s Top CES Products and Takeaways | E2232
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This Week in Startups
AI makes you more creative, AI Roundtable with Steven Johnson and Grant Lee | E2231
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This Week in Startups
2026 Starts with a bang: META AI Drama and Nvidia’s $20B Groq Acquisition | E2230
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This Week in Startups
THE 2025 TWISTY AWARDS! Biggest Trends, Best Guests, Top Name Drops, and more | E2229
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This Week in Startups
Jason’s ultimate dream mega-purchase + Founder Q’s | E2228
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This Week in Startups
Waymo Madness in SF! Why robotaxis clogged the streets | E2227
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This Week in Startups
Level up your copywriting w/ Sam Parr | E2226
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This Week in Startups
INSIDE How AI Startups hire, AI Roundtable with Wade Foster, Mikey Schulman, and Ali Ansari | E2225
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This Week in Startups
Is this the end for the Roomba? Why iRobot went bankrupt | E2224
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This Week in Startups
Disney and OpenAI sign landmark deal… and we saw it coming! | E2223
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This Week in Startups
“The best founders find a way to make it happen”: VC Roundtable with Bryan Kim and David Clark | E2222
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This Week in Startups
FLASHBACK: The future of remote work, juggling APIs, and dream integrations with Wade Foster of Zapier | E2221
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This Week in Startups
What’s REALLY going on with those “ads” in ChatGPT | E2220
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This Week in Startups
Netflix buys WB + why Jason should run Disney | E2219
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This Week in Startups
Getting past the “Cardinal Sins of Delegating” with Jonathan Swanson of Athena | E2218
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This Week in Startups
Monumental Makes Construction Bots Play Nice Together | E2217
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This Week in Startups
Is $MSTR over? Jason takes his victory lap. | E2216
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This Week in Startups
SO MANY THINGS need to go right just so you can watch a TikTok! | E2215
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This Week in Startups
Even great startups sometimes need to pivot (feat. Francisco Cornejo of Theo) | E2214
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This Week in Startups
Jason predicts a “major M&A moment” in the next six months! | E2213
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This Week in Startups
Why data is the biggest AI bottleneck (feat. Arthur Mensch of Mistral AI) | E2212
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This Week in Startups
AI Model Showdown: Grok 4.1 vs. Gemini 3 | E2211
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This Week in Startups
Archer buys an airport, Ramp’s huge raise, RIP KitKat, Bezos returns to the C-Suite, and more | E2210
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This Week in Startups
Stop ghosting your friends with Nox’s RPLY, plus Alloy Automation and a Shopify flashback | E2209
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This Week in Startups
Why We Need Ferries and Tugboats in Space w/ Orbital Operations | E2208
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This Week in Startups
Inside Harvey AI’s $8 billion AI lawyer app, PLUS How OpenRouter unites the LLMs | E2207
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This Week in Startups
IPO Mania hits the TWiST 500! Three companies are ready to go public | E2206
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This Week in Startups
It’s a boat, it’s a plane, it’s REGENT’s Seafarer | E2205
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This Week in Startups
Is investing REALLY the hardest job in tech? A TWIST VC Roundtable (ft. Deedy Das and Jay Eum) | E2204
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This Week in Startups
Sending datacenters into orbit | E2203
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This Week in Startups
What will be OpenAI’s IPO price? Place ya bets! | E2202
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This Week in Startups
Grammarly is now Superhuman! CEO Shishir Mehrotra explains the rebrand | E2201
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This Week in Startups
iPhone Air is “inspiring,” and a first step toward Apple Glasses (w/ Zach Handshoe of SpatialGen) | E2200
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This Week in Startups
Jason Unpacks Sequoia’s New Funds | E2199
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This Week in Startups
If you’re not working 9-9-6, are you working hard enough? | E2198
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This Week in Startups
Amazon’s “Age of Efficiency,” LLM distribution, AI wearable worries, and more with Elad Gil | E2197
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